Through the course of Guzden Varinlioglu's undergraduate education in architecture at Middle East Technical University (METU) and her graduate education in graphic design at Bilkent University, she became interested in digital technology and its contribution to the preservation and presentation of cultural heritage. Her research period at Texas A&M University in 2010 was followed by a Ph.D. degree from the Program of Art, Design, and Architecture at Bilkent University. Her research responded to the lack of systematic methodology for the collection, preservation, and dissemination of data in underwater cultural heritage studies. In 2011, Guzden received a post-doc position in architectural design computing at Istanbul Technical University, and, in 2013-2014, as a visiting scholar, conducted further research at the Centre of Digital Humanities at the University of California (UCLA), Los Angeles. She is currently serving as an Associate Professor of Architecture at the Izmir University of Economics, where she specializes in computational design. At the İzmir University of Economics, she initiated the digital fabrication team (EcoFAB), VRlab, and Digital Humanities Lab. She is currently a Fulbright Scholar at Massachusetts Institute of Technology (MIT) for her project entitled "Stigmergy as a Tool for Uncovering Anatolian Urban Networks of the Past". This research will be further followed by the "Digital Caravanserais Project" at the University of Oxford sponsored by the Chevening Fellowship Programme.